WebJun 15, 2024 · The average final nightly dose at the end of treatment was 8.9 mg; effective doses ranged from 1 to 15 mg. Posttreatment decreases in the mean weekly nightmare frequency, as measured by sleep diary, were greater for the prazosin group than for the placebo group (pretreatment: prazosin 1.0 ± 1.1, placebo 0.4 ± 1.1; posttreatment: … Minipress (prazosin), a drug commonly used to treat high blood pressure and urinary retention, has been shown in some studies to be safe and effective in managing nightmares and sleep disturbances in people with post-traumatic stress disorder (PTSD). See more Historically, only veterans coming home from combat were diagnosed with PTSD. Now, clinicians recognize patients who experience other … See more Prazosin blocks norepinephrine, a stress hormone that affects your brain, at specialized chemical receptors called alpha-1 receptors. Receptors are the sites where cells transmit … See more There are only a few circumstances where you should not take prazosin or use it with caution:5 1. If you have previously had adverse reactions to this or similar medications, don’t take prazosin. 2. If you’re going to have … See more Clinical studies show prazosin might offer other therapeutic benefits to PTSD patients, but the results are mixed. One study suggested that taking prazosin:1 1. Significantly reduced daytime PTSD symptoms when … See more
Prazosin (Minipress): Basics, Side Effects & Reviews - GoodRx
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Alpha blockers - Mayo Clinic
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