Cholyl-l-lysyl-fluorescein

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August undefined, 2024

WebDec 3, 2024 · By incubation with cholyl-l-lysyl-fluorescein (CLF), a fluorescent bile salt derivative that can be taken up by hepatocytes and effluxed into bile canaliculi through ATP-binding cassette subfamily C member 2 (ABCC2, also known as multidrug resistance-associated protein 2) (de Waart et al., 2010), LBDXL 3W hepatocytes demonstrated … WebShop Discovery Life Sciences CHOLYLLYSYLFLUORESCEIN CLF at Fishersci.com

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WebQuantum yield. 0.79001, 0.952. CLF is a fluorescein-labeled bile acid analog that closely parallels the cellular binding and uptake properties of cholic acid derivatives. It is a divalent 'unipolar' anionic fluorescent monohydroxy bile salt analog with physical, biological and … WebMar 28, 2024 · The rhodamine 123 transport assay and active collection of cholyl-lysyl-fluorescein exhibited the specific functions of bile secretion and transportation at day 14 compared to those in monolayer ... fly reel used

Cholyl-lysyl-fluorescein C51H63N3O11S - PubChem

WebAbstract: Background: Cholyl-lysyl-fluorescein (CLF) is a fluorescein-labelled bile acid whose biological behaviour closely resembles that of naturally occurring cholyl glycine. … WebCholy-lysyl-fluorescein (CLF) is a fluorescein-labeled bile acid whose biological behavior closely resembles that of naturally occurring cholyl glycine. CLF is … WebCholyl-L-lysyl-fluorescein (CLF) is a fluorescent bile salt derivative that is being developed as an agent for determining in vivo liver function. However, the mechanisms of uptake and excretion... greenpeace canada members

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Cholyl Lysyl Fluorescein Corning Life Sciences Bioz

WebCholyl-lys-fluorescein (CLF/cholyl-lys-F) is a bile acid (BA) analog, developed to investigate and determine in vivo liver functions. The compound is actually a fluorescein-labeled bile acid derivative with similar properties to … WebCholyl- fluorescence microscopy, either with or without lysyl-fluorescein isothiocyanate (CL-FITC) was washing (L-15 medium) and further incubation, synthesized first by the preparation of cholyl lysine 10 min-3 hr after exposure to the compound. Glass using the method of Tserng et al. (1977). fly repellent for carsWebWe describe the use of a commercially available high content cell imaging algorithm (Cellomics Arrayscan Spot Detector) to quantify biliary excretion of the fluorescent … greenpeace canada history

"WebJul 1, 2010 · Cholyl-l-lysyl-fluorescein (CLF) is a fluorescent bile salt derivative that is being developed as an agent for determining in vivo liver function. However, the mechanisms of uptake and excretion by hepatocytes have not been rigorously studied. We have directly assessed the transport capacity of various hepatobiliary transporters for CLF. " - Cholyl-l-lysyl-fluorescein

Cholyl-l-lysyl-fluorescein

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Web开馆时间：周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 WebThe bile acid derivative may be cholyl-lysyl-fluorescein (CLF). Also claimed is a method of determining the functional activity of the organic anion transporter family (OATP1B3) uptake pathway using a bile acid derivative.

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WebApr 1, 2010 · Cholyl-L-lysyl-fluorescein (CLF) is a fluorescent bile salt derivative that is being developed as an agent for determining in vivo liver function. However, the … WebIn this chapter, we describe methods to culture 3D spheroids of HepaRG cells with extensive bile canalicular structures/networks, image transport of bile acid (cholyl-lysyl-fluorescein) to the bile canaliculi, and measure cholestatic drug-induced cytotoxicity. References

WebWith reference to Figure 32, Cholyl-L-Lysyl-Fluorescein (CLF) is a fluorescein-labelled bile acid whose biological behaviour closely resembles cholyl glycine, and is taken up by the OATP1B3... WebAbstract: Background: Cholyl-lysyl-fluorescein (CLF) is a fluorescein-labelled bile acid whose biological behaviour closely resembles that of naturally occurring cholyl glycine. Aim: The aim of this study was to analyze the CLF plasma …

WebNov 22, 2024 · cholyl-L-lysyl-fluorescein CTNNB1 Catenin beta 1 DG diacylglycerol DNL de novo lipogenesis FA fatty acid FAHFA fatty acid esters of hydroxy fatty acids FPLC fast protein liquid chromatography-based sizeexclusion GTT glucose tolerance test HFD high fat diet HSC hepatic stellate cells IBA1 Ionized Calcium-Binding Adapter Molecule 1 IHC WebNov 30, 1996 · Cholyl lysylfluorescein (CLF) and lithocholyl lysylfluoroscein (LLF) have properties similar to cholylglycine (CG) and glycolithocholate (GLC), respectively. In …

WebFeb 1, 2024 · The fluorescent bile acid-derivative cholyl-l-lysyl-fluorescein (CLF) was used to quantify drug-induced efflux transport inhibition in hepatocytes. …

WebCLF [Cholyl-Lys-Fluorescein] Catalog number: 36701 Unit size: 1 mg Product Details Storage Conditions Freeze (<-15 °C), Minimize light exposure Expiration Date 24 months … fly repellent for catsWebJun 29, 2024 · CuSNPs also introduced hepatocyte spheroid injury through alteration of mitochondrial membrane potential and reactive oxygen species, that could be reversed by N-acetyl- l -cysteine. CuSNPs significantly decreased the activity of BSEP transporter by downregulating its mRNA and protein levels. Activity of the MRP2 transporter remained … fly reno to salt lake cityWebDec 29, 2014 · Liver stem/progenitor cells, with the capacity to produce both mature hepatocytes and cholangiocytes, play essential roles in liver development and tissue regeneration after injury. 1 These cells could be a valuable renewable cell source for cell therapy to treat liver injury and degeneration. greenpeace carbon offsetsWebJul 1, 2010 · Abstract. Cholyl- l -lysyl-fluorescein (CLF) is a fluorescent bile salt derivative that is being developed as an agent for determining in vivo liver … fly repellant campingWebApr 24, 2024 · Cholyl-lysyl-fluorescein (CLF) is a synthetic bile acid analog similar to cholyl glycine, and is taken up by hepatocytes in the liver and excreted into bile … fly repellant candles ikeaWebProduct Name: Cholyl-L-Lysyl-Fluorescein (CLF) Catalog number: 33288 Supplier: Medical Isotopes, Inc. 100 Bridge Street Pelham, NH 03076 USA Tel: +1-603-635-2255 … fly reno to dcWebDec 1, 1991 · Cholyl-lys-F was synthesized employing equimolar amounts of cholyl-lys (sodium salt) and fluorescein isothiocyanate (FITC) in bicarbonate buffer (pH 9.5) over 16 h at room temperature (21 degrees C) with a yield of 70%. The fluorescent property of cholyl-lys-F was similar to fluorescein with a strong apple-green fluorescence. fly repellent for trash can