Dedicator of cytokinesis 2
WebDock11 (Dedicator of cytokinesis), also known as Zizimin2, is a large (~240 kDa) protein involved in intracellular signalling networks. [5] [6] It is a member of the DOCK-D subfamily of the DOCK family of guanine nucleotide exchange factors (GEFs) which function as activators of small G proteins. Dock11 activates the small G protein Cdc42 . Web2 National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, United States. Both Wiskott-Aldrich syndrome (WAS) and dedicator of cytokinesis 8 (DOCK8) deficiency are primary immunodeficiency diseases caused by mutations in genes that result in defective organization of the cytoskeleton in hematopoietic tissues.
Dedicator of cytokinesis 2
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WebHere, we identify the pivotal role of dedicator of cytokinesis 5 (Dock5) in keratinocyte functions contributing to the process of skin wound healing. Specifically, Dock5 is highly upregulated during the proliferative phase of wound repair and is predominantly expressed in epidermal keratinocytes. WebNov 13, 2024 · Dedicator of Cytokinesis 2 (DOCK2) Deficiency Attenuates Lung Injury Associated with Chronic High-Fat and High-Fructose Diet-Induced Obesity. DOCK2 Promotes Pleural Fibrosis by Modulating Mesothelial to Mesenchymal Transition. The role of Dock2 on macrophage migration and functions during Citrobacter rodentium infection.
WebBackground: B-cell receptor (BCR) signaling, combined with CD19 and CD21 signals, imparts specific control of B-cell responses. Dedicator of cytokinesis protein 2 … WebGene ID: 104497852, updated on 12-Mar-2024. Summary Other designations. LOW QUALITY PROTEIN: dedicator of cytokinesis protein 2-like, Dedicator of cytokinesis …
Webdedicator of cytokinesis protein 2, dedicator of cyto-kinesis 2. GeneRIFs: Gene References Into Functions. Extra-hematopoietic immunomodulatory role of the guanine … WebApr 12, 2024 · 2.细胞质分裂作用因子1的环状形式通过海绵化miR-128-3p来抑制有丝分裂相关激酶2的表达，从而促进乳腺癌的进展. 标题：Circular forms of dedicator of cytokinesis 1 promotes breast cancer progression by derepressing never in mitosis related kinase 2 via sponging miR-128-3p. IF：4.109. 期刊：Environ Toxicol
WebView/Edit Human. View/Edit Mouse. Dedicator of cytokinesis protein 10 (Dock10), also known as Zizimin3, is a large (~240 kDa) protein involved in intracellular signalling networks that in humans is encoded by the DOCK10 gene. [5] It is a member of the DOCK-D subfamily of the DOCK family of guanine nucleotide exchange factors, which function as ...
WebApr 6, 2024 · Degradation of extracellular matrix proteins, especially elastin laminae, is the hallmark for AAA development. DOCK2 (dedicator of cytokinesis 2) has shown proinflammatory effects in several inflammatory diseases and acts as a novel mediator for vascular remodeling. However, the role of DOCK2 in AAA formation remains unknown. … crispy shredded chicken peking styleWebGuanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP (By similarity). Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829). crispy shredded chilli beef recipeDock2 (Dedicator of cytokinesis 2), also known as DOCK2, is a large (~180 kDa) protein involved in intracellular signalling networks. It is a member of the DOCK-A subfamily of the DOCK family of guanine nucleotide exchange factors (GEFs) which function as activators of small G proteins. Dock2 specifically … See more Dock2 was first characterised as one of a number of proteins which shared high sequence similarity with the previously described protein Dock180, the archetypal member of the DOCK family. Whereas Dock180 See more Dock2 is part of a large class of proteins (GEFs) which contribute to cellular signalling events by activating small G proteins. In their … See more Like other DOCK-A and DOCK-B subfamily proteins Dock2 GEF activity is specific for Rac. Leukocytes express both Rac1 See more • Overview of all the structural information available in the PDB for UniProt: Q92608 (Dedicator of cytokinesis protein 2) at the PDBe-KB. See more Efficient Dock180 GEF activity in a cellular context is known to require the formation of a complex between Dock180 and its cognate See more Dock2 has been shown to interact with CRKL. See more • Reif K, Cyster J (2003). "The CDM protein DOCK2 in lymphocyte migration". Trends in Cell Biology. 12 (8): 368–73. doi:10.1016/S0962-8924(02)02330-9. PMID 12191913 See more crispy shredded chicken in chilli sauceWebDec 13, 2024 · Overexpression of dedicator of cytokinesis 2 correlates with good prognosis in colorectal cancer associated with more prominent CD8(+) … bufalo club facebookWebNov 17, 2024 · Dedicator of cytokinesis protein 2 (DOCK2) is a member of the cytoskeletal dynamics protein family, and is ubiquitously expressed in hematopoietic … bufalo femeaWebApr 12, 2024 · DOCK2 (dedicator of cytokinesis 2) expression was induced in human pleural fibrosis. ( A ) Hematoxylin and eosin staining in human normal and pleuritis lung suggested increased fibrosis in the visceral pleura of a patient with nonspecific pleuritis versus that in a normal control patient. crispy shredded salt and pepper chickenWebDedicator of cytokinesis protein 2 (DOCK2) is critical for the migration and motility of lymphocytes. Although absence of DOCK2 leads to lymphopenia, little is known about the signaling mechanisms and physiologic functions of DOCK2 in B cells. Objective: crispy shrimp cheeks