WebSoon after the first synthetic estrogen, diethylstilbestrol (DES), was developed in 1938, 1 it was used clinically to prevent complications of pregnancy. 2 In the early 1950s, four clinical... WebDiethylstilbestrol (DES) DES is an obesogenic EDC that promotes weight gain in females, at puberty, after exposure during development ( Newbold et al., 2008, 2009 ). One study in mice showed that DES works to increase obesity by increasing the number of adipocytes in gonadal fat pads ( Angle et al., 2013 ).
What are the Health Risks for DES Daughters and Their …
WebNov 4, 2024 · To date, vaginal/cervical clear cell adenocarcinoma (CCAC) has not been reported in the granddaughters of women treated with diethylstilbestrol (DES) during pregnancy. We present an 8-year-old girl with a history of severe vaginal bleeding who was diagnosed with cervical CCAC. She underwent fertility-sparing surgery and radiotherapy. WebMay 15, 1995 · To review the literature on the long-term health effects of exposure to diethylstilbestrol (DES) among women prescribed DES during pregnancy (DES mothers), among their children exposed inutero to the drug (DES sons and daughters) and among the progeny of these exposed sons and daughters (DES grandchildren). Data … microsoft word if feld
What is DES? DES Action USA
WebTitus-Ernstoff L et al, Menstrual and reproductive characteristics of women whose mothers were exposed in utero to diethylstilbestrol (DES). Int J Epidemiol. 2006. Titus-Ernstoff L et al, Mortality in women given … WebMar 23, 2015 · Diethylstilbestrol (DES) is an artificially created hormone first synthesized in the late 1930s. Doctors widely prescribed DES first to pregnant women to prevent … WebDiethylstilbestrol (DES), the first orally active artificial estrogen ever developed, was prescribed to several million pregnant women during the 1940s through the 1960s in the mistaken belief that it reduced the risk of miscarriage. ... In daughters whose mothers took DES during pregnancy, the drug has been associated with congenital ... microsoft word icon file