Friend erythroleukemia cells

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August undefined, 2024

WebMar 29, 2024 · Erythroleukemia, or acute erythroid leukemia, is a blood and bone marrow cancer. Erythroleukemia is a rare type of acute myeloid leukemia (AML). Only 3-5% of … WebFriend spleen focus-forming virus (SFFV) causes rapid erythroleukemia in mice due to expression of its unique envelope glycoprotein, gp55. Erythroid cells expressing SFFV gp55 proliferate in the absence of their normal regulator erythropoietin (Epo) because of constitutive activation of Epo signal transduction pathways.

Regulation of p53-Mediated Apoptosis and Cell Cycle Arrest by …

WebFeb 1, 1990 · Friend murine leukemia virus (F-MuLV) induces erythroleukemia when inoculated into newborn BALB/c or NIH/Swiss mice. We have molecularly cloned F-MuLV host cell DNA junction fragments from an erythroleukemia cell line induced by F-MuLV to identify cellular genes involved in the leukemogenic process. WebAug 1, 2024 · Erythroleukemia occurs when your body produces a large amount of abnormal red blood cells in the blood and bone marrow.. The bone marrow is a soft … story people quotes family

Induction of Hemoglobin Accumulation in Human K562 Cells by

WebDFMO induced differentiation of MEL cells was sensitive to dexamethasone and 5-bromo-2'-deoxyuridine. (C) 1999 Academic Press. AB - In the present study, the effect of D,L-α-difluoromethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase (ODC), on Friend's murine erythroleukemia (MEL) cell differentiation is investigated. WebBiological activities of arugomycin and its analogues obtained by chemical degradation and modification were evaluated. Differences in the sugar moieties affected their biological activities including induction of differentiation of mouse Friend erythroleukemia cells and mouse myeloid leukemia cells, antitumor activities against sarcoma S-180, Ehrlich … WebAbstract. Friend leukemia cells were cultured in vitro in the presence or absence of agents which induce erythroid differentiation. The cultures were harvested and the degree of … roswithastadt bad gandersheim

Heme biosynthesis in Friend erythroleukemia cells: …

Arugomycin, a new anthracycline antibiotic. III. Biological

WebSep 1, 1981 · We have altered the fatty acid composition of the Friend erythroleukemia cells and studied the effect on the binding parameters of the insulin receptor. Cells were grown for about five generations in media enriched with oleate (a monounsaturated fatty acid) or linoleate (a polyunsaturated fatty acid). Charlotte Friend (March 11, 1921 – January 13, 1987) was an American virologist. She is best known for her discovery of the Friend leukemia virus. She helped to establish the concept of the oncovirus, studied the role of the host immune response in disease development, and helped define modern retrovirology. roswithas teamWebA Friend cell variant (Fw), which is not inducible except in the presence of exogenous hemin, was also studied. All the enzymes of heme synthesis except ferrochelatase were … story performance and event

"WebTransport, unidirectional flux, of a monosaccharide, a nucleoside and three amino acids, all of which enter cells by independent, discrete carriers, was compared at three stages of erythroid maturation, the normal (anucleate) mouse erythrocyte, and in differentiated and undifferentiated Friend erythroleukemia cells. We found specific transport alterations … " - Friend erythroleukemia cells

Friend erythroleukemia cells

DNA damage, demethylation and anticancer activity of DNA ...

WebDifferential stability of host mRNAs in Friend erythroleukemia cells infected with herpes simplex virus type 1 Full Record Related Research Abstract The consequences of herpes simplex virus type 1 infection on cellular macromolecules were investigated in Friend erythroleukemia cells. WebFeb 15, 1980 · Various compounds active in promoting in vitro differentiation of certain murine leukemia cell lines (Friend erythroleukemia cells and mouse myeloid leukemia cells) were tested for their capacity to induce differentiation of HL-60 cells, a human promyelocytic leukemia cell line capable of terminally differentiating in vitro to …

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WebMar 30, 2024 · We have investigated the consequences of activating the Kit signalling pathway by its ligand Steel factor on these opposing functions of the p53 protein in Friend erythroleukemia cells. A temperature-sensitive p53 allele (Val-135) was introduced into the Friend erythroleukemia cell line (DP-16) which lacks endogenous p53 expression. WebFan, Tao, Schmidtmann, Anja, Xi, Sichuan, Briones, Victorino, Zhu, Heming, Suh, Hyung Chan, Gooya, John, Keller, Jonathan R.; Xu, Hong, Ruscetti, Sandra, Muegge ...

WebThe present study was carried out to determine which component of the polycythemic strain of Friend erythroleukemia virus (FV-P)--Friend helper virus [Friend murine leukemia … Webrutherford, t.r., deficient heme synthesis as the cause of non-inducibility of hemoglobin synthesis in a friend-erythroleukemia cell-line, cell 16: 415 (1979). google scholar. …

WebNuclear matrices from undifferentiated and differentiated Friend erythroleukemia cells have been obtained by a method which removes DNA in a physiological buffer. These … WebAbstract. An important limitation in the use of the murine erythroleukenia (MEL) cell system as an in vitro system for the study of terminal erythroid differentiation has been the inability to produce significant numbers of cells which represent the end-point of the pathway in vitro. We show here that a major reason for the failure to observe ...

WebFriend murine erythroleukemia cells (Friend cells) are a transformed line which can differentiate in culture, expressing erythroid characteristics such as hemoglobin …

WebHydrocortisone inhibits DMSO - induced differentiation of Friend erythroleukemia cells. Biochem Biophys Res Commun. 1978 Dec 29; 85 (4):1510–1517. [Google Scholar] Tsiftsoglou AS, Gusella JF, Volloch V, Housman DE. Inhibition by dexamethasone of commitment to erythroid differentiation in murine erythroleukemia cells. story performanceWebPrevious studies have shown that activin A inhibited the colony-forming activity of mouse Friend erythroleukemia cells, however, the mechanism remains unknown. First, we show herein that activin A induced the expression and activated the promoters of α-globin and ζ-globin in K562 cells, confirming that activin A induces erythroid ... roswitha stark bücherWebGrowth in the presence of retinoids was found to induce erythroid differentiation in Friend murine erythroleukemia (MEL) cells in culture. The program of differentiated functions … story people quotesWebBertolini L, Tsuei D, Holland JG, Friend C: Variations in the response of cloned murine Friend erythroleukemia cells to different inducers. In Vitro 17: 284–289, 1981. Google Scholar Carlson DP, Ross J, Wierenga PK, Nijhof W: Expression of the 5′ flanking region of the β major-globin gene in cultured murine erythroid precursor cells. Exp ... ros with gazeboWebAbstract. Cultures of murine Friend erythroleukemia (FL) cells, which are chronically infected with leukemia virus, were inoculated with vaccinia virus. The yield of vaccinia … roswitha zink lichtblickhofWebThese hybrid cells had a phenotype similar to erythroleukemia cells and expressed hemoglobin genes derived from the EC genome. McBurney et al. (1978) concluded that the EC cell genome was reprogrammed to express erythroid genes following cell fusion and interaction with the Friend cell genome. Similar observations were reported in a study of ... story petWebNuclei isolated from VSV-infected Friend erythroleukemia cells were fractionated into a nuclear membrane and a nucleoplasm fraction by DNase digestion and differential centrifugation. G protein was present in the membrane fraction, and M protein was present in the nucleoplasm fraction. Immunofluorescence detection of M protein in the nucleus ... story peter and the wolf