Intrinsically disordered regions 翻译
WebMar 11, 2024 · However, we also found that 37% of all germline pathogenic mutations are located in disordered regions of 96 proteins. Based on the observed-to-expected … Web见维基的解释： An intrinsically disordered protein (IDP) is a protein that lacks a fixed or ordered three-dimensional structure.IDPs cover a spectrum of states from fully …
Intrinsically disordered regions 翻译
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Web另一方面，GPCR家族成员都具有较长的固有无序区（Intrinsically disordered region），主要分布于受体的N端、C端、和受体的ICL3区域。 无序区不仅增加了受体构象的不均一性，而且提供了一些线性模体（motif），以方便下游信号蛋白的识别并形成下游信号 … Webwidespread occurrence of intrinsically disordered proteins or protein segments and their functional relevance has led to the introduction of a new generalization with respect to …
Web蛋白研究过程中，一般认为氨基酸的序列决定了蛋白的结构，结构决定功能（一般指蛋白的三维结构）。然而，近50年的研究中，有一种没有特定三维结构的蛋白不断被研究人员发现，由于这类蛋白无法折叠成稳定的三维 … WebHence, the quest for understanding protein-misfolding disease mechanism might lie in the studies of protein:nucleic acid coacervation. Several proteins with intrinsically disordered regions as well as nucleic acids undergo phase separation in the cellular context, and this process is key to physiological signaling and is related to pathologies.
Web2P269 The update of the IDEAL database, and sequence and structure comparisons of intrinsically disordered regions(22A. Bioinformatics:Structural genomics,Poster) 来自 onAcademic Web查看«Intrinsic region»的翻译、定义、含义、转录和例句，学习«Intrinsic region»的同义词、反义词和发音。
Web基于序列特征的固有无序蛋白结合位点的统计分析xxx 物理与电子信息学院，山东德州253023摘 要 本文以disprot和bsdp数据库中的固有无序蛋白的结合位点为研究对象，构建9种结合位点数据集，利用matlab进行统计结合位点各种氨基
WebIDPs and proteins with intrinsically disordered protein regions (IDPRs) make up around 30% of the human proteome. The key characteristic of IDPs and IDPRs is that they are unable to fold spontaneously into single, well-defined 3D structures, but instead fluctuate between multiple conformations. bypass password on windows without reset diskWeb详细解释：. 内部无序蛋白质/区域 (Intrinsically disordered protein/ region)：包含多种空间结构的蛋白质或在其自然状态下构象可以快速变化的区域。. 分享到：. 编辑词条. bypass patchguardWebSep 27, 2024 · Many MLOs are enriched with intrinsically disordered proteins (IDPs) or proteins that contain intrinsically disordered regions (IDRs) [17,47]. IDPs/IDRs are enriched in amino acid residues such as A, R, G, Q, S, P, E, and K (disorder-promoting) and depleted of amino acid residues such as W, Y, F, V, I, L, C, and N (order-promoting). bypass paths cpuWebIntrinsically disordered proteins (IDPs) in cells phase separate to form diverse membraneless organelles, which have condensed liquid droplet-like properties and often contain multiple IDPs. However, how potential interactions between different IDPs affect the dynamic behavior of these protein droplets is largely unknown. Here, we develop a rapid … bypass patencyWebConformational flexibility conferred though regions of intrinsic structural disorder allows proteins to behave as dynamic molecules. While it is well-known that intrinsically … clothes for thick dachshundsWebSep 26, 2024 · 蛋白研究过程中，一般认为氨基酸的序列决定了蛋白的结构，结构决定功能（一般指蛋白的三维结构）。然而，近50年的研究中，有一种没有特定三维结构的蛋白 … bypass password on startup windows 10WebIn a model study to investigate the consequence of reactions of intrinsically disordered regions (IDRs) of proteins in the context of the formation of highly ordered structures, we found that enzymatic reactions control the secondary structures of peptides during assembly. Specifically, phosphorylation of an α‐helix‐dominant peptide results in mostly … bypass password windows xp