WebA CK19(CreERT) knockin mouse line allows for conditional DNA recombination in epithelial cells in multiple endodermal organs. Cre/LoxP-mediated DNA recombination allows for … Web8 aug. 2024 · Cytokeratin 19 (KRT19) protein is highly expressed in the epithelium of the gastrointestinal (GI) tract, hepatobiliary tissues, and pancreas of humans and mice. In …
Lineage tracing: technology tool for exploring the development ...
Web29 aug. 2024 · To understand the role of cholangiocytic Prom1 in liver fibrosis, we generated cholangiocyte-specific Prom1-deficient mice (Prom1 f/f; Krt19-Cre) by crossing Prom1 f/f mice (f/f) with transgenic ... WebKrt19 marks an early gastrointestinal stem cell during embryonic development of the gut Related to Figure 3. (A)Bacterial artificial chromosome (BAC) transgenic approach used … dr gulati worcester ma lincoln street
Krt19 Targeted Allele Detail MGI Mouse …
Web15 okt. 2024 · Subsequently, Russell et al. used Krt19-Cre mice bred with fluorescent ROSA mice to trace the lineage of BECs. Liver injury was induced by administration of a choline-deficient, ethionine-supplemented (CDE) diet; the mice were then recovered on a normal diet, and BECs were shown to differentiate into hepatocytes to maintain liver … Web12 jul. 2024 · Analysis of the Krt19 Cre tdTomato LSL mice which received AAV8-p21 injection followed by DDC or CDE recovery regime. a. Schematic showing the experimental design of the AAV8-p21 injection followed by DDC recovery regime. b,c. tdTom staining of Krt19 Cre tdTomato LSL mice that received AAV8-p21 injection followed by DDC … Web15 feb. 2024 · Hepatocellular carcinoma (HCC) is one of the most prevalent cancers worldwide and the fourth leading cause of cancer-related death globally. Tumor cells recruit and remodel various types of stromal and inflammatory cells to form a tumor microenvironment (TME), which encompasses cellular and molecular entities, including … dr gulbronson corpus christi